Variable Ratio Mixer

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SIENOX Planetary Vacuum Mixing‑Defoaming Machine SIE‑MIX650


Vacuum Mixer‑Defoamer · Nano‑scale Bubble Removal

500mL Medium‑capacity Dual‑cup + Built‑in Maintenance‑free Vacuum — 99.9% Nano‑scale Bubble Removal

SIE‑MIX650 vacuum mixing‑defoaming machine meets 0‑500 mL mixing and defoaming requirements. Built‑in maintenance‑free vacuum unit combined with revolution‑rotation dual‑power mixing‑defoaming delivers consistent density, uniform dispersion and pure defoaming for multi‑material processing. Suitable for epoxy resin, conductive adhesive, electronic slurry, glue, gel and other materials. Customization available with one‑stop solutions provided.

✓ CE Certification  ✓ FC Certification ✓ ISO9001 Quality System ✓ RoHS Compliance ✓ Customizable Voltage (110V/220V)

Online Message Free Sample Testing Engineer Hotline: 189-2512-9293

Why Must Microbubbles in Materials Be Eliminated?

Residual micro‑bubbles in materials directly affect finished‑product yield and performance

Electronics Industry

Bubbles in potting adhesives cause cavities and gaps after electronic component encapsulation, impairing heat dissipation and insulation reliability. Bubbles in conductive silver paste lead to circuit breaks and resistance fluctuation. Bubbles in circuit‑board laminating adhesives produce bonding‑interface defects and reduce product yield. Medium‑to‑high‑viscosity adhesives tend to entrap air during conventional stirring, with slow natural bubble release and inconsistent encapsulation quality.

Medical Device Industry

Bubbles in medical adhesives weaken bonding strength and biocompatibility. Bubbles in catheter & sensor potting adhesives trigger seal failure and signal interference. Bubbles in in‑vitro diagnostic reagent carriers compromise test accuracy. Medical devices demand high material purity; residual bubbles may cause batch‑to‑batch performance variation and raise quality risks.

Aerospace & Defense Industry

Bubbles in composite matrix resins degrade interlaminar shear strength and fatigue resistance. Bubbles in structural adhesives induce stress concentration at bonding interfaces and harm long‑term reliability. Bubbles in radar‑absorbing coatings alter electromagnetic parameters. The aerospace sector allows minimal internal material defects; micro‑bubble residues may trigger structural‑part failure under extreme operating conditions.

✨ Traditional defoaming challenges: Manual stirring or conventional impeller stirring actively entraps air and generates more bubbles with agitation. Static defoaming takes long time and delivers limited performance for high‑viscosity materials. Conventional vacuum defoaming only removes surface bubbles and fails to eliminate internal micro‑bubbles. The planetary mixing‑defoaming solution separates bubbles while mixing via centrifugal force, enhanced by negative‑pressure vacuum for deep defoaming to realize one‑step mixing and bubble removal.

Why Choose MIX650

Three Core Features Cover Full‑process Requirements for Medium‑capacity Vacuum Defoaming

Built‑in Maintenance‑free Vacuum for Clean Defoaming

Equipped with built‑in vacuum unit, MIX650 requires no regular pump‑oil replacement for maintenance‑free operation with zero environmental pollution, ideal for clean‑room application. Vacuum level adjustable from ‑98 kPa to 0 kPa for flexible parameter setting according to material viscosity and bubble characteristics. The built‑in design eliminates external vacuum pump piping and extra space occupation with high integration. Vacuum defoaming starts right after power‑on to shorten production‑line changeover time.

500 mL Medium‑capacity with Wide‑range Speed Regulation

500 mL dual‑cup configuration fits pilot R&D and continuous production sampling. Dual‑cup simultaneous operation improves batch efficiency. 0‑2000 rpm wide‑range speed covers low‑/medium‑/high‑viscosity materials. Low speed for gentle mixing & defoaming of high‑viscosity adhesives; high speed for fast dispersion of low‑viscosity coating liquids. Synchronized revolution‑rotation dual power completes mixing and defoaming within approx. 1 minute.

Flexible Multi‑segment Program Process Editing

Microcomputer control system stores 100 sets of programs. Each program supports multi‑segment independent time & speed setting for multi‑stage process configuration. User permission management & fault indication support multi‑operator shared usage. Program‑driven operation reduces manual adjustment errors and guarantees consistent batch‑to‑batch performance.

✨ MIX650 integrates three core capabilities: built‑in maintenance‑free vacuum, 500 mL medium‑capacity dual‑cup with wide‑range speed regulation, and flexible multi‑segment program editing. It is suitable for pilot‑scale R&D and production sampling of materials for electronic encapsulation, medical device bonding, aerospace composite materials and more.

Working Principle

Synchronized revolution‑rotation dual‑power operation realizes one‑step mixing and defoaming.

Step 1: Centrifugal Force Generated by Revolution 

High‑speed rotating revolution turntable generates centrifugal force for materials inside containers to drive full‑range convection and achieve macro‑mixing. Meanwhile, centrifugal force pushes low‑density bubbles toward the rotating axis for aggregation and escape. Stable revolution speed ensures consistent mixing performance for each batch. 

Step 2: Shear Force Provided by Rotation

Containers spin around their own axis to generate directional shear force for breaking agglomerated particles and realizing micro‑dispersion. Precisely calculated fixed revolution‑rotation speed ratio ensures high‑efficiency full‑range mixing. Shear force thins bubble membranes and accelerates bubble rupture. No built‑in impeller contacts materials, lowering risk of metal‑chip contamination and preserving material chemical properties. 

Step 3: Deep Defoaming Under Vacuum Negative Pressure

The built‑in vacuum unit draws gas to form negative‑pressure environment, reducing pressure difference inside and outside bubbles so deep‑seated micro‑bubbles expand and escape. Adjustable vacuum from ‑98 kPa to 0 kPa adapts to defoaming requirements of various‑viscosity materials. Built‑in vacuum unit runs maintenance‑free with no regular pump‑oil replacement and zero environmental pollution. 


Synchronized revolution‑rotation combined with vacuum negative pressure completes the full‑flow "Mixing → Dispersion → Vacuum Defoaming" inside sealed containers with built‑in maintenance‑free vacuum.

Working Principle of Vacuum Mixer‑Defoamer.jpg


Technical Specifications

Complete Technical Specifications Overview, Customizable on Demand

ModelSIE‑MIX650
Mixing Capacity0–500 mL (standard container) * Larger volume customizable
Container TypeTest tube / Can / Cup; adapters for syringe & cartridge available
Quantity of Containers1 or 2 cans (user‑selectable)
Max Speed0 – 2000 RPM (stepless adjustable)
Revolution / Rotation RatioFixed planetary ratio
Vacuum DegreeStandard: –98 kPa / Optional: –100 kPa
Control SystemTouch screen, stores up to 100 recipe sets
Power Supply220V, 50/60Hz (110V US‑JP standard customizable)
Overall Dimension(W×D×H)580 × 560 × 760 mm
Net Weight145 kg
Certifications CE, FC, ISO9001, RoHS Compliance

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FAQ - Frequently Asked Questions

Answers to common questions about product performance and everyday process selection

  • What is the working principle of a centrifugal defoaming machine?

    Principle of centrifugal defoaming machine: The bubbles are released by the downward principle of gravity.

  • How is the after-sales service?

    The company has professional after-sales service personnel, 24-hour dedicated service, and one-on-one technical support to solve your worries.

  • Why choose SIENOX?

    There are many reasons for choosing SIENOX, and the following are some of the main reasons:

    1. Professionalism: Our team consists of a group of professional individuals with rich experience and knowledge in their respective fields. We not only understand industry trends and best practices, but also provide practical and feasible solutions.

    2. Service quality: We focus on customer needs and satisfaction, and are always committed to providing high-quality services. We not only respond quickly to customer needs, but also provide customized services according to their requirements.

    3. Reliability: We adhere to the principles of integrity and professionalism, always adhering to commitments and agreements. Our work methods and deliverables comply with industry standards and best practices, enabling our clients to trust us.

    4. Innovation: We continuously explore new methods and tools to provide better services and meet customer needs. We encourage innovation and experimentation, and are willing to accept challenges and change.

    5. Cost effectiveness: We provide cost-effective services that not only help customers save costs, but also improve efficiency and productivity. We always prioritize the interests of our customers and provide them with the best solutions.

    6. Teamwork: We believe in the power and value of teamwork, and our team members support, collaborate, and respect each other. We establish close cooperative relationships with customers, partners, and other stakeholders to achieve common goals.

    The above are just some of the reasons for choosing us. We believe there are many other advantages and values that can be provided to customers. If you are looking for a professional, reliable, and high-quality service provider, we look forward to working with you.


  • How does the stirring and defoaming machine work?

    The SIENOX stirring and defoaming machine performs defoaming through centrifugal force at revolution and stirring through shear force formed by revolution and rotation,

    Assisted by a vacuum pump to extract gas and achieve a vacuum state, removing nanoscale tiny bubbles. No contact with materials, no secondary pollution, and no secondary waste.

  • What is the function of a defoaming machine?

    A defoaming machine is a device used to remove bubbles from liquids. Its function is to assist in the liquid mixing, reaction, coating, printing, infusion and other process steps in the production process, avoiding the generation of bubbles and their impact on the final product. In many industrial and laboratory environments, removing bubbles is essential as they may have a negative impact on product quality, such as affecting surface tension and stability. Defoaming machines typically use various techniques such as vibration, ultrasound, centrifugation, etc. to achieve effective bubble removal. It has a wide range of applications, including but not limited to semiconductors, solar energy, optics, biotechnology, materials science, etc.

Technical Specification List

Full‑line standardized specifications for accurate process evaluation and equipment selection

ModelSIE‑MIX60SIE‑MIX650SIE‑MIX90
Mixing Capacity0–300 mL (standard container) * Customizable0–500 mL (standard container) * Customizable0–1000 mL (standard container) * Customizable
Container TypeTest tube / Can / Cup; adapters for syringe & cartridge availableTest tube / Can / Cup; adapters for syringe & cartridge availableTest tube / Can / Cup; adapters for syringe & cartridge available
Quantity of Containers1  or 2 cans (user‑selectable)1  or 2 cans (user‑selectable)1  or 2 cans (user‑selectable)
Max Speed0 – 3000 RPM (stepless adjustable)0 – 2000 RPM (stepless adjustable)0 – 2000 RPM (stepless adjustable)
Revolution / Rotation RatioFixed planetary ratioFixed planetary ratioFixed planetary ratio
Vacuum DegreeStandard: –98 kPa / Optional: –100 kPaStandard: –98 kPa / Optional: –100 kPaStandard: –98 kPa / Optional: –100 kPa
Control SystemTouch screen, stores up to 100 recipe setsTouch screen, stores up to 100 recipe setsTouch screen, stores up to 100 recipe sets
Power Supply220V, 50/60Hz (110V US‑JP standard customizable)220V, 50/60Hz (110V US‑JP standard customizable)220V, 50/60Hz (110V US‑JP standard customizable)
Overall Dimension(W×D×H)510 × 430 × 500 mm580 × 560 × 760 mm610 × 560 × 780 mm
Net Weight95 kg145kg153 kg
CertificationsCE, FCCE, FCCE, FC

*** The above are typical models only. Customized solutions are available upon customer requirements.


Multi‑Industry Solutions

Provide customized solutions to meet comprehensive demands from cutting‑edge R&D to large‑scale mass production

Electronic Materials.jpg

Electronics Industry

Epoxy Potting Adhesive, Conductive Silver Adhesive, Electronic Slurry, UV Adhesive, Thermal‑conductive Gel

Aerospace.jpg

Aerospace & Defense Industry

Composite Matrix Resin, Structural Adhesive, Radar‑absorbing Coating, Functional Coating Liquid

Medical Device 02.jpg

Medical Device Industry

Medical Adhesive, Sensor Potting Adhesive, Catheter Coating Liquid, Diagnostic Reagent Carrier

Petrochemical.jpg

Chemical Industry

Resin Casting Compound, Resin Solution, Catalyst Slurry, Reactive Adhesive

Adhesives.jpg

Adhesive & Sealant Industry

Structural Adhesive, Sealant, Conductive Adhesive, High‑temperature Adhesive

Photosensitive Materials.jpg

3D Printing Industry

Photosensitive Resin, Functional Ink, Ceramic Slurry, Composite Prepreg

Comprehensive Equipment Operation Demo Videos

Gain intuitive, clear, dynamic insight into synchronous defoaming with planetary centrifugal force and high negative pressure.

Measured Defoaming‑Process Performance

Thoroughly eliminate material bubbles, voids and stratification

UV Adhesive Defoaming.jpg

UV Adhesive

Epoxy Resin Defoaming.jpg

Epoxy Resin

Polymer Materials.jpg

Polymer Materials

Gel Defoaming 02.jpg

Pharmaceutical Gel

Silver Paste Mixing‑Defoaming.jpg

Silver Paste Material

Battery Slurry Mixing‑Defoaming.jpg

Battery Slurry


Measured Data Comparison

Quantifiable Effects Validated by Test Data

Material TypeStatus Before TreatmentAfter MIX650 Treatment
Epoxy Potting AdhesiveDense internal bubbles, ~5% encapsulation void rate, unstable insulation performanceBubbles removed, encapsulation void rate <0.5%, stable insulation property
Lithium‑ion Battery Cathode SlurryHeavy internal bubbles, ~6% coating pinhole rate, large thickness deviationBubbles removed, coating pinhole rate <1%, uniform thickness
Thermal‑conductive GreaseNumerous bubbles, agglomerated thermal‑conductive powder, thermal conductivity deviation ±15%Uniform powder dispersion, bubbles removed, thermal conductivity deviation ±3%

* Internal lab test data. Actual improvement varies with material formula. Contact sales for real customer cases.

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